{"id":12056,"date":"2021-01-05T16:50:16","date_gmt":"2021-01-05T21:50:16","guid":{"rendered":"https:\/\/www.highpoint.edu\/library\/?p=12056"},"modified":"2021-11-11T09:24:49","modified_gmt":"2021-11-11T14:24:49","slug":"pandemics-past-historys-most-notorious-plagues","status":"publish","type":"post","link":"https:\/\/www.highpoint.edu\/library\/2021\/01\/05\/pandemics-past-historys-most-notorious-plagues\/","title":{"rendered":"Pandemics Past: History&#8217;s Most Notorious Plagues"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-12059 size-full\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/resized-image-Promo.jpeg\" alt=\"resized image Promo\" width=\"580\" height=\"280\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/resized-image-Promo.jpeg 580w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/resized-image-Promo-300x145.jpeg 300w\" sizes=\"auto, (max-width: 580px) 100vw, 580px\" \/><\/p>\n<p><span style=\"font-weight: 400\">Pandemics have plagued humans from the beginning of time.\u00a0 The very existence of humans living in communities among other humans and animals nearly guarantees that people will get sick from communicable and pervasive diseases. America and North Carolina have not been immune to many of those disease outbreaks from their very beginnings.<\/span><\/p>\n<p><span style=\"font-weight: 400\">From ancient times through the 19th Century, most epidemics were caused by bacteria from exposure to contaminated water, food, or animal borne parasites.\u00a0 Bubonic plague, cholera, and typhoid fever are prime examples.\u00a0 After the development of better sanitation and modern medicines like penicillin, pandemics developed through viruses that spread person to person or animal to person.\u00a0 Influenza, polio, HIV, and viral hemorrhagic fever are examples that still survive in parts of the world.<\/span><\/p>\n<figure id=\"attachment_12065\" aria-describedby=\"caption-attachment-12065\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-12065 size-medium\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/smallpox-300x158.jpg\" alt=\"smallpox\" width=\"300\" height=\"158\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/smallpox-300x158.jpg 300w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/smallpox.jpg 310w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-12065\" class=\"wp-caption-text\">New York City children wait in line<br \/>for immunization shots, c. 1944. <br \/>Courtesy of Library of Congress.<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400\">One of the first recorded epidemics in North America occurred when a\u00a0 sailor infected with smallpox sailed into Boston harbor aboard the H.M.S. Seahorse in 1721.\u00a0 He had infected most of his shipmates and at least one other person before the town realized the problem and began quarantining residents.\u00a0 By that time it had already spread through churches, shops, and homes.\u00a0 Cotton Mather, a Puritan minister and member of the science-oriented British Royal Society, suggested they try inoculation of smallpox virus, which had been successful in eastern Europe. Ironically, the doctors of Boston fought against the practice, while the clergy thought it might be helpful.\u00a0 By the end of the year, nearly ten percent of the population had died and around fifty percent of infected people recovered but had long term repercussions from the disease.\u00a0 Around 250 people were inoculated, with only six succumbing to the disease.\u00a0 The outcome became one of the first debates between science and religion in our country (Williams, 15).<\/span><\/p>\n<figure id=\"attachment_12068\" aria-describedby=\"caption-attachment-12068\" style=\"width: 172px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-12068\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/yellow-fever.jpg\" alt=\"yellow fever\" width=\"172\" height=\"225\" \/><figcaption id=\"caption-attachment-12068\" class=\"wp-caption-text\">Death as a sailor<br \/>bringing Yellow Fever<br \/>to New York, c.1864.<br \/>Frank Leslie\u2019s <br \/>Illustrated Newspaper.<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400\">Yellow fever came to the Americas from West Africa during the slave trade beginning in the early 17th century.\u00a0 Transmitted through mosquitoes, it hit major ports along the Atlantic, predominantly Boston, New York, and Philadelphia.\u00a0 In 1793 in Philadelphia, it affected the newly formed government and began heated debate over how epidemics spread. Arguments over the merits of quarantining versus sanitation ensued with little resolve. Yellow fever struck again during the Civil War with both southern and northern troops succumbing to the disease.\u00a0 When federal troops took over New Orleans, which had been ravaged by the disease, General Benjamin Butler enforced a strict quarantine and had soldiers clean the streets (Humphreys).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tuberculosis is another disease that spread rapidly across the globe in the 19th and 20th centuries.\u00a0 It was not until the late 1800\u2019s when Robert Koch isolated the bacteria causing tuberculosis that the medical community began to understand how it spread from exposure to coughing or sneezing from an infected person. At the turn of the century, it is believed that eighty percent of the U.S. population under age twenty was infected and it was the leading cause of death.\u00a0 The only remedy was to isolate those infected in \u201csanatoriums\u201d.\u00a0 Even today with antibiotics and vaccinations, tuberculosis is still present, although not as deadly as it once was (Davidson).<\/span><\/p>\n<figure id=\"attachment_12071\" aria-describedby=\"caption-attachment-12071\" style=\"width: 300px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-12071 size-medium\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/uscamphospital45influenzaward-300x210.jpg\" alt=\"uscamphospital45influenzaward\" width=\"300\" height=\"210\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/uscamphospital45influenzaward-300x210.jpg 300w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/uscamphospital45influenzaward-280x195.jpg 280w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/uscamphospital45influenzaward.jpg 366w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-12071\" class=\"wp-caption-text\">U.S. Army Camp Hospital No. 45,<br \/>Aix-Les-Bains, France, <br \/>Influenza Ward No. 1. C.1918. <br \/>Courtesy National Park Service.<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400\">In the 20th century, the most prominent pandemic to occur was the influenza outbreak of 1918 that resulted from infected World War I soldiers returning home from the war. Lasting for two years in four waves, it infected nearly 500 million people worldwide and even though record keeping at the time was minimal, perhaps 20-25 million died from the virus. In the U.S., around 25 million became infected, with a death rate between 500,000-800,000. And surprisingly,\u00a0 more than fifty percent of the deaths were between the ages of 20 and 40.\u00a0 Even some of those who survived suffered complications.\u00a0 Encephalitis lethargica or \u201csleeping sickness\u201d affected nearly five million people who had survived the Spanish flu.\u00a0 This was a neurological problem that left victims with high fevers, coma-like sleeping disorders, and movement impairments that would now be considered pre-Parkinson\u2019s disease complications.\u00a0 Oliver Sacks recounted the study of this phenomena in his book, \u201c<\/span><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/5551843707\"><span style=\"font-weight: 400\">Awakenings<\/span><\/a><span style=\"font-weight: 400\">\u201d, which would later be made into a <\/span><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/40987802\"><span style=\"font-weight: 400\">movie<\/span><\/a><span style=\"font-weight: 400\">.<\/span><\/p>\n<p><span style=\"font-weight: 400\">In the last century, other viruses and diseases have plagued the world such as polio and HIV\/AIDS. According to the North Carolina History Project, North Carolina was hit hardest by polio in the 1940\u2019s, with the worst year being 1948 when over 2500 children were stricken with the disease and 143 died. The town of Hickory was so hard hit that it was nicknamed \u201cPolio City\u201d (Koon).<\/span><\/p>\n<figure id=\"attachment_12074\" aria-describedby=\"caption-attachment-12074\" style=\"width: 263px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-12074 size-full\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/polio.jpg\" alt=\"polio\" width=\"263\" height=\"192\" \/><figcaption id=\"caption-attachment-12074\" class=\"wp-caption-text\">Rare photograph of Roosevelt in<br \/>a wheelchair, with Ruthie Bie and Fala<br \/>(1941). Wikipedia.com images.<\/figcaption><\/figure>\n<p><span style=\"font-weight: 400\">Probably the most famous person to have been a victim of polio was Franklin D. Roosevelt, who<\/span><span style=\"font-weight: 400\">, <\/span><span style=\"font-weight: 400\">in 1921,contracted \u201cinfantile paralysis\u201d at the age of 39. His struggle with polio brought the disease heightened public awareness, and his efforts to help sufferers eventually led to the founding of the March of Dimes, an organization that played a pivotal role in the eventual development of viable vaccines (Turner).<\/span><\/p>\n<p><span style=\"font-weight: 400\">Human Immunodeficiency Virus (HIV) is believed to have developed in the early 20th century when the virus passed from primates to humans on the African continent.\u00a0 It wasn\u2019t until the 1980\u2019s that researchers began to see the mysterious virus spreading around the globe. Spread through body fluids, there is still no cure for HIV\/AIDS and more than a million people die worldwide.\u00a0 As treatments and therapeutic remedies continue to improve, however, more people are living longer with the disease.<\/span><\/p>\n<p><span style=\"font-weight: 400\">As we struggle to deal with the Covid-19 pandemic, it is important to remember that humans have been struggling with bacteria and viruses since time began. We will get through this crisis with the help of science and perseverance, but it is good to look back to see how far we have come.\u00a0\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><strong>Further Reading<\/strong><\/h3>\n<p><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/648922587\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12077\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1-196x300.jpg\" alt=\"book1\" width=\"130\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1-196x300.jpg 196w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1-668x1024.jpg 668w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1-768x1178.jpg 768w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1-1002x1536.jpg 1002w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1-1336x2048.jpg 1336w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1-620x950.jpg 620w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book1.jpg 1650w\" sizes=\"auto, (max-width: 130px) 100vw, 130px\" \/><\/a><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/30701925\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12080\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book2-198x300.jpg\" alt=\"book2\" width=\"132\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book2-198x300.jpg 198w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book2.jpg 264w\" sizes=\"auto, (max-width: 132px) 100vw, 132px\" \/><\/a><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/149010628\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12083\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-200x300.jpg\" alt=\"book3\" width=\"133\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-200x300.jpg 200w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-682x1024.jpg 682w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-768x1153.jpg 768w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-1023x1536.jpg 1023w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-1365x2048.jpg 1365w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-633x950.jpg 633w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3-520x780.jpg 520w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book3.jpg 1645w\" sizes=\"auto, (max-width: 133px) 100vw, 133px\" \/><\/a><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/36501356\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12086\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book4-195x300.jpg\" alt=\"book4\" width=\"130\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book4-195x300.jpg 195w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book4.jpg 325w\" sizes=\"auto, (max-width: 130px) 100vw, 130px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/45306695\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12089\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book5-200x300.jpeg\" alt=\"book5\" width=\"133\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book5-200x300.jpeg 200w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book5.jpeg 260w\" sizes=\"auto, (max-width: 133px) 100vw, 133px\" \/><\/a><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/38519046\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12092\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book6-184x300.jpg\" alt=\"book6\" width=\"123\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book6-184x300.jpg 184w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book6.jpg 291w\" sizes=\"auto, (max-width: 123px) 100vw, 123px\" \/><\/a><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/17385275\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12095\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book7-193x300.jpg\" alt=\"book7\" width=\"128\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book7-193x300.jpg 193w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book7.jpg 255w\" sizes=\"auto, (max-width: 128px) 100vw, 128px\" \/><\/a><a href=\"https:\/\/hpulibraries.on.worldcat.org\/oclc\/44089242\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-12098\" src=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-201x300.jpg\" alt=\"book8\" width=\"134\" height=\"200\" srcset=\"https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-201x300.jpg 201w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-685x1024.jpg 685w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-768x1148.jpg 768w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-1027x1536.jpg 1027w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-1370x2048.jpg 1370w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-635x950.jpg 635w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8-520x780.jpg 520w, https:\/\/www.highpoint.edu\/library\/files\/2021\/04\/book8.jpg 1531w\" sizes=\"auto, (max-width: 134px) 100vw, 134px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h3><strong>Short List of Sources<\/strong><\/h3>\n<p><span style=\"font-weight: 400\">Davidson, Tish, et al. &#8220;Tuberculosis.&#8221; <\/span><i><span style=\"font-weight: 400\">Gale Encyclopedia of Public Health<\/span><\/i><span style=\"font-weight: 400\">, 1st edition, 2013. <\/span><i><span style=\"font-weight: 400\">Credo Reference<\/span><\/i><span style=\"font-weight: 400\">, <a href=\"https:\/\/libproxy.highpoint.edu\/login?url=https:\/\/search.credoreference.com\/content\/entry\/galegph\/tuberculosis\/0?institutionId=2970\">https:\/\/libproxy.highpoint.edu\/login?url=https:\/\/search.credoreference.com\/content\/entry\/galegph\/tuberculosis\/0?institutionId=2970<\/a>. Accessed 17 Dec. 2020.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Humphreys, Margaret. &#8220;Yellow Fever.&#8221; <\/span><i><span style=\"font-weight: 400\">The Oxford Encyclopedia of the History of American Science, Medicine, and Technology<\/span><\/i><span style=\"font-weight: 400\">, edited by Hugh Richard Slotten, Oxford University Press, Inc., 1st edition, 2014. <\/span><i><span style=\"font-weight: 400\">Credo Reference<\/span><\/i><span style=\"font-weight: 400\">, <a href=\"https:\/\/libproxy.highpoint.edu\/login?url=https:\/\/search.credoreference.com\/content\/entry\/ouposmat\/yellow_fever\/0?institutionId=2970\">https:\/\/libproxy.highpoint.edu\/login?url=https:\/\/search.credoreference.com\/content\/entry\/ouposmat\/yellow_fever\/0?institutionId=2970<\/a>. Accessed 17 Dec. 2020.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Koon, David J.\u00a0 \u201cPolio in North Carolina\u201d. North Carolina History Project. John Locke Foundation, 2016, <\/span><a href=\"https:\/\/northcarolinahistory.org\/encyclopedia\/polio-in-north-carolina\/\"><span style=\"font-weight: 400\">https:\/\/northcarolinahistory.org\/encyclopedia\/polio-in-north-carolina\/<\/span><\/a><span style=\"font-weight: 400\">.\u00a0 Accessed 17 Dec., 2020.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Turner, Julie. &#8220;Polio.&#8221; <\/span><i><span style=\"font-weight: 400\">Global Social Issues: An Encyclopedia<\/span><\/i><span style=\"font-weight: 400\">, edited by Christopher G. Bates, and James Ciment, Routledge, 1st edition, 2013. <\/span><i><span style=\"font-weight: 400\">Credo Reference<\/span><\/i><span style=\"font-weight: 400\">, <a href=\"https:\/\/libproxy.highpoint.edu\/login?url=https:\/\/search.credoreference.com\/content\/entry\/sharpesi\/polio\/0?institutionId=2970\">https:\/\/libproxy.highpoint.edu\/login?url=https:\/\/search.credoreference.com\/content\/entry\/sharpesi\/polio\/0?institutionId=2970<\/a>. Accessed 18 Dec. 2020.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Williams, Tony J.. <\/span><i><span style=\"font-weight: 400\">America&#8217;s Beginnings : The Dramatic Events that Shaped a Nation&#8217;s Character<\/span><\/i><span style=\"font-weight: 400\">, Rowman &amp; Littlefield Publishers, 2010.<\/span><i><span style=\"font-weight: 400\"> ProQuest Ebook Central<\/span><\/i><span style=\"font-weight: 400\">, <\/span><a href=\"https:\/\/ebookcentral.proquest.com\/lib\/highpoint-ebooks\/detail.action?docID=1043754\"><span style=\"font-weight: 400\">https:\/\/ebookcentral.proquest.com\/lib\/highpoint-ebooks\/detail.action?docID=1043754<\/span><\/a><span style=\"font-weight: 400\">.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong>-blog post by Melinda Pennington, Evening Reference Librarian<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pandemics have plagued humans from the beginning of time.\u00a0 The very existence of humans living in communities among other humans and animals nearly guarantees that people will get sick from communicable and pervasive diseases. America and North Carolina have not been immune to many of those disease outbreaks from their very beginnings. From ancient times&#8230;<\/p>\n","protected":false},"author":62,"featured_media":12059,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_hpuaeo_plugin_post_data":"","_hpuaeo_plugin_meta_tags":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[176,94],"tags":[269,377,89],"class_list":["post-12056","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-books-and-ebooks","category-library-displays","tag-book-lists","tag-covid-19","tag-history"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6.1 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Pandemics Past: History&#039;s Most Notorious Plagues - Library<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.highpoint.edu\/library\/2021\/01\/05\/pandemics-past-historys-most-notorious-plagues\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pandemics Past: History&#039;s Most Notorious Plagues\" \/>\n<meta property=\"og:description\" content=\"Pandemics have plagued humans from the beginning of time.\u00a0 The very existence of humans living in communities among other humans and animals nearly guarantees that people will get sick from communicable and pervasive diseases. America and North Carolina have not been immune to many of those disease outbreaks from their very beginnings. 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