Research Administration and Sponsored Programs


High Point University recognizes the necessary roles that live animals play in research and teaching, and a concurrent responsibility to treat animals humanely. Our mission is to contribute to science education and the advancement of scientific knowledge while maintaining the most humane care and treatment of animal subjects. All High Point University faculty, staff, and students whose research or teaching involves live vertebrate animals in some way, whether in the lab or in the field, must be familiar with and conform to institutional, federal, and state regulations governing those activities. HPU established an Institutional Animal Care and Use Committee (IACUC) to ensure the proper care, use and humane treatment of animals used in research and teaching. The IACUC sets policies and procedures in accord with the United States Department of Agriculture’s Animal Welfare Regulations (which implement the Animal Welfare Act), Public Health Services Policy on Humane Care and Use of Laboratory Animals (Public Health Service Policy) and the National Academy of Science’s National Research Council’s Guide for the Care and Use of Laboratory Animals (Guide).

Submitting an Animal Use and Care Protocol

No use of a live vertebrate animal is permitted for research or teaching purposes without an IACUC Approved Animal Care and Use Protocol. Procedures for submitting an Animal Use and Care Protocol for IACUC review are given below:.

Complete the electronic version of the Animal Use and Care Protocol Proposal Form, sign it, have it signed by your Department Chair, and submit as an Email attachment to Please include “IACUC Protocol Proposal” in RE: line.

Please note:

  • Proposed Protocols to be reviewed should be received by the IACUC more than thirty (30) days prior to the date approval is required.
  • IACUC approval must be received before housing aimals in any HPU facility.
  • An IACUC approved protocol is valid for a maximum of 3 years.
  • Commencement, expiration, and annual review dates dates will be assigned for the project based on the approval date. A copy of the Approved Protocol will be returned to the principal investigator or instructor.

HPU’s Protocol Form is designed, in part, to help assure that the following points as recommended by the Guide are addressed in the preparation and review of animal use and care protocols:

    • Rationale and purpose of the proposed use of animals
    • Justification of the species and number of animals requested. Whenever possible, the number of animals requested should be justified statistically. Availability or appropriateness of the use of less-invasive procedures, other species, isolated organ preparation, cell or tissue culture, or computer simulation (see Appendix A of the Guide, “Alternatives”)
    • Adequacy of training and experience of personnel in the procedures used
    • Unusual housing and husbandry requirements
    • Appropriate sedation, analgesia, and anesthesia, (Scales of pain or invasiveness might aid in the preparation and review of protocols; see Appendix A of the Guide, “Anesthesia, Pain and Surgery.”)
    • Unnecessary duplication of experiments
    • Conduct of multiple major operative procedures
    • Criteria and process for timely intervention, removal of animals from a study, or euthanasia if painful or stressful outcomes are anticipated
    • Postprocedure care
    • Method of euthanasia or disposition of animal
    • Safety of working environment for personnel

Animal Use and Care Protocol Proposal Form

Post-Approval Review

Protocol approvals are valid for a maximum of three years. The Principal Investigator or instructor must request IACUC approval for any significant departure from the original protocol by submitting a written description of the changes to the IACUC Chair at The Principal Investigator or instructor must verify the status of the project annually by completing and submitting to the IACUC the Annual Protocol Renewal Form. A completed electronic version of the Annual Protocol Review Form should be signed and submitted as an email attachment to Protocol approvals will be canceled for discontinued projects or projects that deviate significantly from the approved protocol.

Annual Protocol Renewal Form

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